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Mo’Nique has let it be known that she has no love for Empire director Lee Daniels, and his decision to snub her from the winning TV series–and Hollywood in general.

During a recent sitdown with TMZ Live, the Oscar winner took off her gloves (and makeup) to put it all out in the open.

Mo’Nique just did something remarkable … fearlessly speaking out about her feud with Lee Daniels — one of the most powerful directors in Hollywood — for claiming she’s been blackballed.

The 2010 Oscar winner for Best Supporting Actress came on TMZ Live to reveal what went down when her “Precious” director Daniels — who’s also co-creator of “Empire” — called her to say Hollywood execs think she’s “difficult” … and don’t want to work with her.

Actors almost never take on a director in public, but this interview is different — Mo’Nique did not back down to Daniels. As for what started the beef — Mo’Nique thinks it’s all because she didn’t name drop someone during her Oscar speech. Check out the clip.

Politics … they’re not just for D.C.

According to Mo, things went sour following her Precious acceptance speech for Best Supporting Actress when she failed to thank Daniels in any capacity. While it may be petty, she’s definitely not the first one to feel Hollywood’s cold shoulder.

Check out Mo’Nique’s TMZ Live interview below.

Photos: TMZ