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Legendary boxer Manny “Pac Man” Pacquiao may have to end his storied career after reportedly exhibiting early signs of Parkinson’s disease. A neurologist in the pugilist’s native Philippines said he’s observed stuttering and hand twitching in the former world champion on Thursday. 

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If you haven’t heard by now, Manny Pacquiao got his a** handed to him at the MGM Grand in Las Vegas Saturday (Dec.  8). The bout between the 33-year-old and opponent Juan Manuel Marquez  came to an abrupt end when Pacquiao was knocked out in round sixth.

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Manny Pacquiao and Juan Manuel Marquez squared off at the MGM Grand last night. The first three of their fights ended in a draw and two decisions favoring Pac Man. But on the fourth go around Marquez knocked Pacquiao smooth out.

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Just in time for this weekend’s epic rematch bout with Juan Manuel Marquez, Jay-Z’s Life + Times unveils the first installment of A Day In the Life: Manny Pacquiao, a two part mini-documentary on the prolific boxer and philanthropist. The film details Manny Pacquiao, his history fighting Marquez and his preparation for the upcoming fourth rematch.