5. Dayton, OH
Population Change 2000-2009: -11,961
Population Percent Change 2000-2009: -7.21%
Home Vacancy: 18.9%
Through the first half of the 20th century, Dayton had one of the healthiest manufacturing industries. It had more GM autoworkers than any city outside of Michigan during World War II. In the past 50 years, Mead has merged with West Virginia Paper and moved to Richmond, and GM has closed one plant after another in the city.